Text reading "Clinical science that's tested. The proof is in the products."

Background

Independent Clinical Trial

The objective of this study was to precisely test the tolerability and efficacy of Ao Skincare's PM Serum-Shot with strict clinical-dermatological test criteria. During the clinical trial, skin elasticity (skin strength), skin roughness and digital photographic recording using the VISIA® System were measured and studied over time.

Results

100% had an improvement in Skin Elasticity.

This clinical study, conducted under dermatological supervision, evaluated skin elasticity following product application. Over four weeks, 20 subjects applied the test product to their faces once every evening. An assessment of skin elasticity, performed under clinical-dermatological oversight, revealed a 29% improvement in skin elasticity in the test area.


100%

of study participants had an increase in Skin Elasticity

Up to


56%

increase in Skin Elasticity in just 4 weeks

Average improvement of


29%

across all study participants, over 4 weeks

Results

Before & Afters

The efficacy of the product was evaluated by the additional acquisition of digital pictures (macro pictures). The images below are photos using the Visia® system.

Before

Example 1

Close-up of a person's closed eye, showing wrinkles and fine lines with arrows pointing to them, before and after treatment.

After 4 weeks use

Close-up showing the skin around a closed eye with visible fine lines and wrinkles. Arrows indicate areas of interest, possibly before and after treatment.

Before

Example 2

Close-up of a closed eye with visible wrinkles and arrows pointing to the wrinkles around the eye.

After 4 weeks use

Close-up of a closed human eye with visible wrinkles and white arrows pointing to fine lines and skin texture.

Before

Example 3

Close-up of a person's closed eye and upper cheek showing skin tags and wrinkles, with white arrows pointing to the skin tags.

After 4 weeks use

Close-up of an eye with skin blemishes and wrinkles, arrows pointing to moles or spots on the skin.

Exemplary photos of volunteers before application and after four weeks of application. Arrowheads indicate an improvement of wrinkle depth.

Results

100% had an improvement in Skin Roughness.

The evaluation of skin roughness, performed under clinical-dermatological control, indicated a reduction in skin roughness by 14% in the test area.


100%

of study participants had a reduction in Skin Roughness

Up to


24%

decrease in Skin Roughness in just 4 weeks

Average improvement of


14%

across all study participants, over 4 weeks

Simple but potent formulations.

Less ingredients and even fewer that are known to cause skin sensitivities. Compared to a leading clinical skincare brand, Ao PM Serum has up to 3.6x fewer ingredients.

Number of ingredients in formulation

3.6x

Dermalogica Overnight Retinol Repair

Ao Skincare PM Serum

Number of ingredients known to cause irritation, hormone disruption or worse*

18

Dermalogica Overnight Retinol Repair

0

Ao Skincare PM Serum

*Comparing EWG toxicity and irritation rating scale

Clinical Science

science that’s tested.
The proof is in the products.

Comparison chart of skincare products featuring Paula's Choice Resist Retinol, Skin Medica Retinol Complex, Dermalogica Retinol Repair, and Ao PM Serum. The chart evaluates features like processing method, vitamin A content, usability, active boosters, antioxidants, dermatologist development, active ingredients, barrier ingredients, customer ratings, clinical trials, elasticity improvement, photos, airless components, ingredient transparency, usage duration, and price per month. Ao PM Serum shows more check marks indicating positive attributes, with a 5-star rating and $31/month price for 4 months of use.

Results

100% had no skin irritation

Of the study participants, 60% reported having sensitive skin. Over a four-week period, 20 subjects applied our PM Serum-Shot once daily in the evening to their faces. No significant skin reactions were observed in the test area from a clinical-dermatological perspective, demonstrating excellent product tolerance.

Excellent product tolerance

“No signs of irritation or allergic reactions, such as contact dermatitis, were detected. Thus, from a dermatological standpoint, the tested product does not show a high potential for irritation when used as directed. Overall, the product was tolerated extremely well.” Dermatest

Senstitive skin

Clinical study participants who had sensitive skin

Clinical study participants who did not have sensitive skin

60%

40%

Irritation from use

0%

Ao PM Serum-Shot

92% felt their skin was more soft & supple or hydrated after 4 weeks*

Customer Feedback

After 1 week


Donut chart showing 85% improvement, 10% dry/rough, 5% no change.

After 4 weeks


Donut chart showing 93% improvement in blue and 7% no change in dark blue, with labels for improvement, dry/rough, and no change.

*In-house qualitative study, 80 subjects, 2016